Recognizes an epitope between amino acid residues 6-57 within the N-terminal (NT) region of Tropomodulin 1 (Tmod1), otherwise known as erythrocyte tropomodulin (E-Tmod).

Tmod1 is a sarcomeric protein highly expressed by erythrocytes, heart and skeletal muscle, which binds to and caps pointed ends of actin filaments to prevent thin filament elongation. The binding of the N-terminal region of Tmod1 with the actin-binding protein tropomyosin blocks the elongation and depolymerization of actin filaments, contributing to the geometry of the membrane skeleton.

Functionally inhibits the binding of Tmod1 to tropomyosin.

Suitable for use in Immunofluorescence, FLISA, and Western Blot. Other applications not tested.

Optimal dilutions to be determined by the researcher.

Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight™650 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Note: Applications are based on unconjugated antibody.

Recombinant protein corresponding to chicken Tropomodulin 1 at N-terminal. Species sequence homology: Birds, fish, insect, reptiles and mammals.

Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™650.

Purified by Protein A affinity chromatography from tissue culture supernatant.

Recognizes chicken Tropomodulin 1.