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216750 Rat Anti-JAM-A (Junctional Adhesion Molecule A)

Specifications
Clone Type
Monoclonal
Host
Rat
Source
Mouse
Isotype
IgG2
Clone Number
14L654
Grade
Affinity Purified
Applications
WB
Crossreactivity
Mo
Shipping Temp
Blue Ice
Storage Temp
-20°C

Functional adhesion molecule A is found in endothelial and epithelial tight junctions and is involved in the inflammatory enlistment of mononuclear cells containing LFA-1. JAM-A is linked to atherogenesis, platelet activation, transmigration of leukocytes and angiogenesis. JAM-A is also found to be important in the development of many different organ systems, and is mostly expressed in the epithelial parts and the embryonic vasculature. JAM-A is indicated to play a role in epithelial permeability, inflammation and proliferation in the intestine, aiding in homeostasis.

Applications
Suitable for use in Western Blot. Other applications not tested.
Recommended Dilution
Western Blot: 1:500-1:1000 Optimal dilutions to be determined by the researcher.
Storage and Stability
Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Immunogen
Recombinant protein corresponding to extracellular domain of mouse Junctional adhesion molecule A (JAM-A).
Form
Supplied as a lyophilized powder in PBS. Reconstitute with 200ul sterile PBS.
Purity
Purified by Protein A/G affinity chromatography.
Specificity
Recognizes mouse JAM-A in Western blotting.
Conjugates
Pricing
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