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245637-ML650 Mouse Anti-EIF2AK2 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2, EIF2AK1, MGC126524, PKR, PRKR) (MaxLight 650)

Specifications
References
Brand
MaxLight™
Clone Type
Monoclonal
Host
Mouse
Conjugate
MaxLight™650
Isotype
IgG1,k
Clone Number
1D11
Grade
Purified
Applications
FLISA IF IHC WB
Accession #
NP_002750
Shipping Temp
Blue Ice
Storage Temp
4°C Do Not Freeze
Notes
Preservative Free
Eukaryotic Translation Initiation Factor 2-alpha Kinase 2, EIF2AK1, MGC126524, PKR, PRKR

MaxLight™650 is a new Far-IR stable dye conjugate comparable to Alexa Fluor™647, DyLight™649, Cy5™ and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (655nm); Emission (676nm); Extinction Coefficient 250,000.

Mouse monoclonal antibody raised against a partial recombinant EIF2AK2.
Applications
Suitable for use in Immunofluorescence, Western Blot, Immunohistochemistry. Other applications not tested.
Recommended Dilution
Optimal dilutions to be determined by the researcher.
AA Sequence
MAGDLSAGFFMEELNTYRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNMouse monoclonal antibody raised against a partial recombinant EIF2AK2.KLAVEILNKEKKAVSPLLLTTTNSSEGLSMGN
Storage and Stability
Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight™650 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
Immunogen
EIF2AK2 (NP_002750, 1aa-100aa) partial recombinant protein with GST tag. MW of the GST tag alone is 26kD.
Form
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™650.
Purity
Purified
Specificity
Recognizes EIF2AK2.
References
No references available
USBio References
1.PKR negatively regulates leukemia progression in association with PP2A activation, Bcl-2 inhibition and increased apoptosis. Cheng X, Bennett RL, Liu X, Byrne M, Stratford May WBlood Cancer J. 2013 Sep 6;3:e144. doi: 10.1038/bcj.2013.42. 2.PKR regulates proliferation, differentiation and survival of murine hematopoietic stem/progenitor cells.Liu X, Bennett RL, Cheng X, Byrne M, Reinhard MK, May WS JrBlood. 2013 Feb 14. 3.Increased Expression of the dsRNA-Activated Protein Kinase PKR in Breast Cancer Promotes Sensitivity to Doxorubicin.Bennett RL, Carruthers AL, Hui T, Kerney KR, Liu X, May WS Jr.PLoS One. 2012;7(9):e46040. doi: 10.1371/journal.pone.0046040. Epub 2012 Sep 24.
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