The family of p21-activated protein kinases (PAKs) is composed of serine-threonine kinases. A novel human PAK-interacting protein, hPIP1, interacts with PAK1 and inhibits the Cdc42/Rac-stimulated kinase activity suggesting that hPIP1 is a negative regulator of PAK and PAK signaling pathways.

Suitable for use in Western Blot. Other applications not tested.

Western Blot: 1:500-1:1000 Optimal dilutions to be determined by the researcher.

Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight™650 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Note: Applications are based on unconjugated antibody.

Human PIP-1

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™650.

Purified by immunoaffinity chromatography.

Recognizes human PIP-1.