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302479 Rabbit Anti-H1FNT (Testis-specific H1 Histone, Haploid Germ Cell-specific Nuclear Protein 1, Histone H1t2, H1FNT, HANP1)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
Q75WM6
Isotype
IgG
Grade
Affinity Purified
Applications
WB
Crossreactivity
Hu
Gene ID
341567
Gene #
H1FNT
Shipping Temp
Blue Ice
Storage Temp
-20°C

Essential for normal spermatogenesis and male fertility. Required for proper cell restructuring and DNA condensation during the elongation phase of spermiogenesis. Involved in the histone- protamine transition of sperm chromatin and the subsequent production of functional sperm. Binds both double-stranded and single-stranded DNA, ATP and protamine-1 (By similarity).

Applications
Suitable for use in Western Blot. Other applications not tested.
Recommended Dilution
Western Blot: 1:2000 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH conjugated synthetic peptide corresponding to aa59-93 from human H1FNT.
Form
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Recognizes human H1FNT. Species Crossreactivity: human
References
Huang C.Q.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.|Scherer S.E.,et al.Nature 440:346-351(2006).|Tanaka H.,et al.Int. J. Androl. 29:353-359(2006).|Martianov I.,et al.Proc. Natl. Acad. Sci. U.S.A. 102:2808-2813(2005).|
USBio References
No references available
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