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302545 Rabbit Anti-MAML2 (Mastermind-like Protein 2, Mam-2, MAML2, KIAA1819)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
Q8IZL2
Isotype
IgG
Grade
Affinity Purified
Applications
WB
Crossreactivity
Hu
Gene ID
84441
Gene #
MAML2
Shipping Temp
Blue Ice
Storage Temp
-20°C

Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Potentiates activation by NOTCH3 and NOTCH4 more efficiently than MAML1 or MAML3.

Applications
Suitable for use in Western Blot. Other applications not tested.
Recommended Dilution
Western Blot: 1:2000 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH conjugated synthetic peptide corresponding to aa780-814 at the Central region of human MAML2.
Form
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Recognizes human MAML2. Species Crossreactivity: human
References
Tonon G.,et al.Nat. Genet. 33:208-213(2003).|Tonon G.,et al.Nat. Genet. 33:408-408(2003).|Nagase T.,et al.DNA Res. 8:85-95(2001).|Taylor T.D.,et al.Nature 440:497-500(2006).|Enlund F.,et al.Exp. Cell Res. 292:21-28(2004).|
USBio References
No references available
Conjugates
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