KS6A1, MAPKAP-K1a, RPS6KA1, RSK-1, RSK1
Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB. Silverman E, et al. Mol Cell Biol. 2004 Dec; 24(24): 10573-10583. Itoh S, et al. J Biol Chem 2005 Jun 24; 280(25): 24135-24142 Eisenmann KM, et al. Cancer Res 2003 Dec 01; 63(23): 8330-7
Applications
Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended Dilution
Western Blot: 1:500-1:1000 Immunohistochemistry: 1:50-1:100 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Peptide corresponding to the sequence around aa350-354 (R-D-S-P-G) derived from human p90RSK.
Form
Supplied as a liquid in PBS (without Mg2+ and Ca2+), pH 7.4, 0.02% sodium azide, 50% glycerol.
Purity
Purified by immunoaffinity chromatography.
Specificity
Species Crossreactivity: mouse and rat