FGF-2, bFGF, Heparin-binding growth factor 2, HBGF-2
Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. {ECO:0000269 PubMed:1721615, ECO:0000269 PubMed:8663044}.
Biological Activity
Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine balb/c 3T3 cells is less than 0.05ng/ml, corresponding to a specific activity of ＞ 2.0x10e7 IU/mg.
Sequence
MPALPEDGGS GAFPPGHFKD PKRLYCKNGG FFLRIHPDGR VDGVREKSDP HIKLQLQAEE RGVVSIKGVC ANRYLAMKED GRLLASKCVT DECFFFERLE SNNYNTYRSR KYTSWYVALK RTGQYKLGSK TGPGQKAILF LPMSAKS
PubMed ID
3472745; 3780670; 2538817; 19054851; 15815621; 1785797; 2435575; 1721615; 8564983; 3579930; 2435284; 3964259; 3732516; 1417798; 1885605; 8663044; 10e358027; 11509569; 11964394; 16257968; 18669637; 20230531; 15863030; 20094046; 22321063; 1769963; 1707542; 1849658; 1702556; 7691311; 11390973; 8885834
Storage and Stability
Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Source
Recombinant, E. coli
Purity
≥96% as determined by SDS-PAGE and HPLC.
Form
Lyophilized from 0.2um filtered PBS, pH 7.4
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Form
Lyophilized from 0.2um filtered PBS, pH 7.4
Purity
≥96% as determined by SDS-PAGE and HPLC.
TDS
NCBI
UniProt
Tech Support
Customer Service
