This gene encodes a type II transmembrane glycoprotein that is the highly polymorphic Kell blood group antigen. The Kell glycoprotein links via a single disulfide bond to the XK membrane protein that carries the Kx antigen. The encoded protein contains sequence and structural similarity to members of the neprilysin (M13) family of zinc endopeptidases. [provided by RefSeq]
Applications
Suitable for use in Western Blot. Other applications not tested.
Recommended Dilution
Optimal dilutions to be determined by the researcher.
AA Sequence
MEGGDQSEEEPRERSQAGGMGTLWSQESTPEERLP VEGSRPWAVARRVLTAILILGLLLCFSVLLFYNFQNCG PRPCETSVCLDLRDHYLASGNTSVAPCTDFFSFACGR AKETNNSFQELATKNKNRLRRILEVQNSWHPGSGEEK AFQFYNSCMDTLAIEAAGTGPLRQVIEELGGWRISGK WTSLNFNRTLRLLMSQYGHFPFFRAYLGPHPASPHTP VIQIDQPEFDVPLKQDQEQKIYAQIFREYLTYLNQLGTL LGGDPSKVQEHSSLSISITSRLFQFLRPLEQRRAQGKL FQMVTIDQLKEMAPAIDWLSCLQATFTPMSLSPSQSLV VHDVEYLKNMSQLVEEMLLKQRDFLQSHMILGLVVTL SPALDSQFQEARRKLSQKLRELTEQPPMPARPRWMK CVEETGTFFEPTLAALFVREAFGPSTRSAAMKLFTAIR DALITRLRNLPWMNEETQNMAQDKVAQLQVEMGASE WALKPELARQEYNDIQLGSSFLQSVLSCVRSLRARIVQ SFLQPHPQHRWKVSPWDVNAYYSVSDHVVVFPAGLL QPPFFHPGYPRAVNFGAAGSIMAHELLHIFYQLLLPGG CLACDNHALQEAHLCLKRHYAAFPLPSRTSFNDSLTFL ENAADVGGLAIALQAYSKRLLRHHGETVLPSLDLSPQQ IFFRSYAQVMCRKPSPQDSHDTHSPPHLRVHGPLSST PAFARYFRCARGALLNPSSRCQLW
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Protein corresponding to aa1-732 from full length human KEL.
Form
Supplied as a liquid in PBS, pH 7.4.
Specificity
Recognizes human KEL
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