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501134 Mouse Anti-ACE2

Specifications
References
Clone Type
Monoclonal
Host
Mouse
Source
Human
Swiss Prot
Q9BYF1
Isotype
IgM,k
Clone Number
881CT16.4.4
Grade
Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_068576.1
Gene ID
59272
Gene #
ACE2
Shipping Temp
Blue Ice
Storage Temp
-20°C
Angiotensin-converting enzyme 2, ACE-related carboxypeptidase, Angiotensin-converting enzyme homolog, ACEH, Metalloprotease MPROT15, Processed angiotensin-converting enzyme 2, ACE2

Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses.

Applications
Suitable for use in ELISA, Western Blot. Other applications not tested.
Recommended Dilution
Western Blot: 1:1000 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, ce
Immunogen
Purified protein corresponding to human ACE2, fused to His-Tag.
Form
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity
Purified by Euglobin precipitation.
Specificity
Recognizes human ACE2.
References
1. Donoghue M., et al. Circ. Res. 87:E1-E9(2000).|2. Tipnis S.R., et al. J. Biol. Chem. 275:33238-33243(2000).|3. Douglas G.C., et al. Endocrinology 145:4703-4711(2004).|4. Itoyama S., et al. Am. J. Med. Genet. A 136:52-57(2005).|5. Suzuki Y., et al. Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases.
USBio References
No references available
Conjugates
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