CAK, CD 167, CD167, CD167 antigen-like family member A, CD167a, Cell adhesion kinase, DDR 1, DDR, DDR1, DDR1_HUMAN, Discoidin domain receptor, Discoidin domain receptor tyrosine kinase 1, Discoidin receptor tyrosine kinase, Discoidin receptor tyrosine kinase isoform a, EDDR 1, EDDR1, Epithelial discoidin domain receptor 1, Epithelial discoidin domain-containing receptor 1, Epithelial specific receptor kinase, HGK2, Mammarian carcinoma kinase 10, Mammary carcinoma kinase 10, MCK-10, MCK10, NEP, Neuroepithelial tyrosine kinase, Neurotrophic tyrosine kinase receptor type 4, NTRK 4, NTRK4, OTTHUMP00000029343, OTTHUMP00000029344, OTTHUMP00000029345, OTTHUMP00000029346, OTTHUMP00000029347, OTTHUMP00000164863, OTTHUMP00000164867, OTTHUMP00000222080, Protein-tyrosine kinase 3A, Protein-tyrosine kinase RTK-6, PTK 3, PTK 3A protein tyrosine kinase 3A, PTK3, PTK3A, Receptor tyrosine kinase NEP, RTK 6, RTK6, TRK E, TRKE, Tyrosine kinase DDR, Tyrosine kinase receptor E, Tyrosine-protein kinase CAK

Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases.