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573498 Rabbit Anti-PRPF8

Specifications
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
Q6P2Q9
Isotype
IgG
Grade
Affinity Purified
Applications
E IF
Crossreactivity
Hu
Shipping Temp
Blue Ice
Storage Temp
-20°C
Pre-mRNA-processing-splicing factor 8 (220kD U5 snRNP-specific protein) (PRP8 homolog) (Splicing factor Prp8) (p220), PRPF8, PRPC8

Functions as a scaffold that mediates the ordered assembly of spliceosomal proteins and snRNAs. Required for the assembly of the U4/U6-U5 tri-snRNP complex. Functions as scaffold that positions spliceosomal U2, U5 and U6 snRNAs at splice sites on pre-mRNA substrates, so that splicing can occur. Interacts with both the 5' and the 3' splice site.

Applications
Suitable for use in ELISA and Immunofluorescence. Other applications not tested.
Recommended Dilution
Immunofluorescence: 1:50-1:200 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Recombinant protein corresponding to aa2037-2170 from human Pre-mRNA-processing-splicing factor 8 protein.
Form
Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Purity
Purified by Protein G affinity chromatography.
Specificity
Recognizes human PRPF8.
Conjugates
Pricing
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