NT-proBNP is a cleavage product during the proteolytic activation of BNP. NT-proBNP is a secreted protein which is a member of the natriuretic peptide family, which is predominantly secreted from the cardiac ventricles in response to volume and pressure overload. NT-proBNP is more stable than BNP in serum, and has become a useful biomarker of heart failure.

Suitable for use in FLISA and Western Blot. Other applications have not tested.

Optimal dilutions to be determined by the researcher.

Sp2/0 myeloma cells with spleen cells from Balb/c mice.

Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight™550 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Note: Applications are based on unconjugated antibody.

aa13-27 from N-terminal of Pro Brain Natriuretic Peptide

Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™550.

Purified by Protein A affinity chromatography.

Recognizes the amino-terminal fragment at aa13-20 of human pro-brain natriuretic peptide at ~9kD.