Caspase 1, CT

Brand

MaxLight™

Clone Type

Polyclonal

Host

Rabbit

Source

Human

Swiss Prot

P29466

Conjugate

MaxLight™550

Isotype

IgG

Grade

Affinity Purified

Applications

IHC WB

Crossreactivity

Shipping Temp

Blue Ice

Storage Temp

4°C Do Not Freeze

Notes

Preservative Free
BSA Free

MaxLight™550 is a new Yellow-Green photostable dye conjugate comparable to Alexa Fluor™546, 555, DyLight™549 , Cy3™, TRITC and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (550nm); Emission (575nm); Extinction Coefficient 150,000.

Applications

Suitable for use in Immunohistochemistry (paraffin) and Western Blot. Other applications not tested.

Recommended Dilution

Immunohistochemistry (paraffin): 2.0ug/ml Western Blot: 0.5-1ug/ml Optimal dilutions to be determined by the researcher.

Storage and Stability

Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight™550 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Note: Applications are based on unconjugated antibody.

Immunogen

A 16aa peptide located near human Caspase-1 carboxy terminus.

Form

Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™550.

Purity

Purified by immunoaffinity chromatography.

Specificity

Recognizes human CASPASE-1 (C-TERMINAL).

References

1. Ghayur, T. et al. (1997) Caspase-1 processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma production. Nature. 386: 619-623. 2. Fantuzzi, G. et al. (1998) Interleukin-18 regulation of interferon gamma production and cell proliferation as shown in interleukin-1beta-converting enzyme (caspase-1)-deficient mice. Blood. 91: 2118-2125. 3. Kostura, M.J. et al. (1989) Identification of a monocyte specific preinterleukin 1beta convertase activity. P.N.A.S USA 86: 5227-5231. 4. Miura, M. et al. (1993) Induction of apoptosis in fibroblasts by IL-1 beta-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3. Cell. 75: 653-660.

USBio References

No references available

Product	Size	List	Your Price	Qty	Ext Price
Subtotal:	Subtotal:
Subtotal:	Subtotal:
Total Coupon Savings:	Total Coupon Savings:	()
Your cart is currently empty.
- Coupon Code

Product

Size

List

Your Price

Qty

Ext Price

Subtotal:

Total Coupon Savings:

()

Your cart is currently empty.

- Coupon Code

Brand

Clone Type

Host

Source

Swiss Prot

Conjugate

Isotype

Grade

Applications

Crossreactivity

Shipping Temp

Storage Temp

Notes

References

USBio References

Conjugates

Pricing

Order

Cart Summary

Recently Viewed

Special Offers

Contact Us

Site Map

Technical Resources

Distributors

Payment Methods