CD1a is a ~49kDa single pass type 1 transmembrane glycoprotein containing a single Ig-like domain, expressed in association with beta 2 microglobulin. CD1a is expressed strongly by cortical thymocytes, and also by Langerhans cells and interdigitating cells. CD1a is involved in the presentation of lipids and glycolipids to NK cells.

Suitable for use in Flow Cytometry and Immunohistochemistry. Other applications not tested.

Flow Cytometry: 10ul labels 10e6 cells in 100ul Immunohistochemistry: Frozen sections Optimal dilutions to be determined by the researcher.

NS1/Ag4.1 myeloma cells with spleen cells from Balb/c mice.

Skin

Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight™650 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Note: Applications are based on unconjugated antibody.

Human thymocytes

Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™650.

Purified by Ion Exchange chromatography

Recognizes human CD1. Species Crossreactivity: canine and Cynomolgus monkey