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C2443-86K Mouse Anti-CD98 (4F2 Cell Surface Antigen Heavy Chain, 4F2 Heavy Chain Antigen, 4F2hc, 4T2HC, CD98 Heavy Chain, CD98HC, Lymphocyte Activation Antigen 4F2 Large Subunit, MDU1, Monoclonal 44D7, NACAE, Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport) Member 2, SLC3A2)

Specifications
References
Clone Type
Monoclonal
Host
Mouse
Source
Human
Isotype
IgM
Clone Number
IPO-T10
Grade
Purified
Applications
FC IHC
Crossreactivity
Hu
Shipping Temp
Blue Ice
Storage Temp
-20°C
CD98 Antigen, 4F2, 4F2 Heavy Chain, Antigen Defined by Monoclonal Antibody 4F2 Heavy Chain, Antigen Identified by Monoclonal Antibodies 4F2 TRA1.10 TROP4 and T43, Solute Carrier Family 3 Member 2

The CD98 molecule is a heterodimer made of a disulfide-linked glycosylated heavy chain of approximately 80-90kD and a non-glycosylated light chain. The heavy chain is a type II integral membrane protein containing a 50-81aa NH2-terminal cytoplasmic domain, a single transmembrane sequence, and a large extracellular domain. CD98 is detected on monocytes and activated cells.

Applications
Suitable for use in Flow Cytometry and Immunohistochemistry. Other applications not tested.
Recommended Dilution
Immunohistochemistry: frozen sections Optimal dilutions to be determined by the researcher.
Hybridoma
P3X63-Ag8.653 myeloma cells with spleen cells from Balb/c mice.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Native human leukocytes
Form
Supplied as a liquid in PBS, 0.05% sodium azide.
Purity
Purified
Specificity
Recognizes human CD98.
References
1. The Sixth International Workshop and Conference on Human Leukocyte Differentiation Antigens, Kobe, Japan 1996, in press (Garland Publishing, Inc, London).
USBio References
No references available
Conjugates
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