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C2446-02AX Mouse Anti-CD104 (CD104 Antigen, GP150, Integrin beta4, Integrin beta-4, ITGB4)

Specifications
References
Clone Type
Monoclonal
Host
Mouse
Source
Human
Isotype
IgG2a
Clone Number
7H228
Grade
Affinity Purified
Applications
FC WB
Crossreactivity
Hu
Shipping Temp
Blue Ice
Storage Temp
-20°C
Notes
Preservative Free

Human CD104 (beta 4 integrin) associates with the alpha 6 integrin chain and binds to laminin and epiligrin and likely has cell-cell adhesion functions. CD104 is involved in signal transduction (4).

Applications
Suitable for use in Western Blot and Flow Cytometry. Other applications not tested.
Recommended Dilution
Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
UM-SCC-1, human squamous cell carcinoma
Form
Supplied as a liquid in 50mM sodium phosphate, pH 7.5, 100mM potassium chloride, 50mM sodium chloride. No preservative added.
Purity
Purified by Protein A affinity chromatography.
Specificity
Recognizes human CD104 adhesion molecule.
References
1. K.A. Kimmel & T.E. Carey, (1986) Cancer Res 46: 3614-3623, 2. C VanWaes, et al, (1991) Cancer Res 51: 2395-2402, 3. Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p. 1655-1663, 1667-1668, 4. F. Mainiero, et al, (1995) EMBO J 14: 4470-4481, 5. S Tyagi, AR Ahmed, et al. (1996) PNAS 93(25): 14714-14719.
USBio References
No references available
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