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C2549-18A3 Mouse Anti-CD270 (ATAR, Herpes Virus Entry Mediator A, Herpes virus Entry Mediator A, HveA, HVEM, LIGHTR, Tumor Necrosis Factor Receptor Superfamily Member 14, TNFRSF14, Tumor Necrosis Factor Receptor-like 2, TR2, UNQ329/PRO509) (PE)

Specifications
References
Clone Type
Monoclonal
Host
Mouse
Source
Human
Conjugate
PE
Isotype
IgG2a,k
Clone Number
7H150
Grade
Purified
Applications
FC FLISA
Crossreactivity
Hu
Shipping Temp
Blue Ice
Storage Temp
4°C Do Not Freeze

Human CD270 (Herpes Virus Entry Mediator, TNFRSF14, ATAR, LIGHTR, TR2) is a 36kD type I membrane protein that has been found on a broad range of lymphoid tissues. Its ligands include the TNF Ligand family members LTalpha and LIGHT, and the CD28/Ig Superfamily member BTLA (2).

Applications
Suitable for use in FLISA and Flow Cytometry. Other applications not tested.
Recommended Dilution
Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for 6 months at 4°C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light.
Immunogen
Recombinant corresponding to human CD270
Form
Supplied as a liquid in 50mM sodium phosphate, pH 7.5, 500mM potassium chloride, 150mM sodium chloride, 0.2% BSA, 0.04% sodium azide and 15% glycerol. Labeled with R-Phycoerythrin (PE).
Purity
Purified
Specificity
Recognizes recombinant human CD270 in ELISA, and binds to CD270 present on human U-937 cell surface in Flow Cytometry.
References
1. Hsu H, et al. (1997) J Biol Chem 272:13471, 2. Gonzalez LC, et al. (2005) PNAS 102(4): 1116-1121.
USBio References
No references available
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