FEN1 is a member of the XPG/RAD2 endonuclease family which has an important role in lagging strand DNA synthesis and base excision repair. It is hypothesised that FEN1 may play a role in the inhibltion of triplet repeat expansion.

Suitable for use in Immunoprecipitation and Western Blot. Other applications not tested.

Immunoprecipitation: 4ug/mg Western Blot: 1:5000-1:30,000 Optimal dilutions to be determined by the researcher.

Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight™650 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Note: Applications are based on unconjugated antibody.

Synthetic peptide corresponding to a region within the N terminal domain of human FEN1 (locus link ID 2237).

Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™650.

Purified by immunoaffinity chromatography.

Recognizes human FEN1.