Ras-GTPase-activating protein SH3-domain-binding protein; GAP binding protein; RasGAP-associated endoribonuclease G3BP: This protein is one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Suitable for Western Blot and Immunoprecipitation. Other applications not tested.

Optimal dilutions to be determined by researcher.

Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight 650 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap..

Note: Applications are based on unconjugated antibody.

Synthetic peptide corresponding to C-terminus of human GTPase Activating Protein (KLH).

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™650.

Purified by Protein G affinity chromatography.

Recognizes human GTPase Activating Protein (GAP). May crossreact with other species.