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H7960-14B Goat Anti-HIP14 (Palmitoyltransferase ZDHHC17, Huntingtin Yeast Partner H, Huntingtin-interacting Protein 14, HIP-14, Huntingtin-interacting Protein 3, HIP-3, Huntingtin-interacting Protein H, Putative MAPK-activating Protein PM11, Putative NF-kappa-B-activating Protein 205, Zinc Finger DHHC Domain-containing Protein 17, DHHC-17, ZDHHC17, HIP3, HYPH, KIAA0946, HSPC294)

Specifications
References
Clone Type
Polyclonal
Host
Goat
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Bo Ca Hu Mo Rt
Accession #
NP_056151.2
Gene ID
23390
Shipping Temp
Blue Ice
Storage Temp
-20°C

Palmitoyltransferase specific for a subset of neuronal proteins, including SNAP25, DLG4/PSD95, GAD2, SYT1 and HD. May be involved in the sorting or targeting of critical proteins involved in the initiating events of endocytosis at the plasma membrane. Has transforming activity. Mediates Mg2+ transport.

Applications
Suitable for use in ELISA and Western Blot. Other applications not tested.
Recommended Dilution
ELISA: 1:8000 Western Blot: 1-3ug/ml, observed in human and mouse brain lysates on ~70kD bands Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic peptide corresponding to CYDQISGSGYQLV, from ZDHHC17, at C-terminal (NP_056151.2).
Form
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Purity
Purified by immunoaffinity chromatography.
Specificity
Recognizes human ZDHHC17. Species Crossreactivity: Mouse. Species sequence homology: Bovine, canine and rat.
References
1. Huang K, Yanai A, Kang R, Arstikaitis P, Singaraja RR, Metzler M, Mullard A, Haigh B, Gauthier-Campbell C, Gutekunst CA, Hayden MR, El-Husseini A. Huntingtin-Interacting Protein HIP14 Is a Palmitoyl Transferase Involved in Palmitoylation and Trafficking of Multiple Neuronal Proteins. Neuron. 2004 Dec 16;44(6):977-86.
USBio References
No references available
Conjugates
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