Interleukin 2

Clone Type

Monoclonal

Host

Mouse

Source

Human

Conjugate

Isotype

IgG1

Clone Number

7H154

Grade

Affinity Purified

Applications

Crossreactivity

Shipping Temp

Blue Ice

Storage Temp

4°C Do Not Freeze

The cytokine human Interleukin-2 (IL-2) is a 15kD protein expressed upon activation by peripheral TH1 cells, medullary thymocytes, and a subset of large granular lymphocytes. Secreted IL-2 stimulates proliferation and lymphokine production by T cells, B cells and NK cells.

Applications

Suitable for use in Flow Cytometry. Other applications not tested.

Recommended Dilution Optimal dilutions to be determined by the researcher.

Storage and Stability

May be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only pror to immediate use. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity.

Immunogen

Recombinant human IL-2

Form

Supplied as a liquid in 50mM Sodium Phosphate pH 7.5, 500mM Potassium Chloride, 150mM NaCl, 15% Glycerol, 0.2% BSA, 0.04% NaN3.

Purity

Purified by Protein A affinity chromatography.

Specificity

Recognizes human Interleukin 2.

References

1.S.L. Swain (1991) Curr Opin Immunol 3-304-310. |2. A.K. Abbas, et al, (1996) Nature 383: 787-793. 3. A. Rebollo, et al, (1996) Advan Immunol 63: 127-196.|