Defects in KLHDC8B are a cause of Hodgkin lymphoma (HL) [MIM:236000]. A malignant disease characterized by progressive enlargement of the lymph nodes, spleen and general lymphoid tissue, and the presence of large, usually multinucleate, cells (Reed-Sternberg cells). Reed-Sternberg cells compose only 1-2% of the total tumor cell mass. The remainder is composed of a variety of reactive, mixed inflammatory cells consisting of lymphocytes, plasma cells, neutrophils, eosinophils and histiocytes. Note=A chromosomal aberration disrupting KLHDC8B has been found in a family with the nodular sclerosis type of classic Hodgkin lymphoma. Translocation t(2,3)(q11.2;p21.31).
| Product | Size | List | Your Price | Qty | Ext Price | ||||
|---|---|---|---|---|---|---|---|---|---|
| Subtotal: | Subtotal: | ||||||||
| Subtotal: | Subtotal: | ||||||||
| Total Coupon Savings: | Total Coupon Savings: | () | |||||||
| Your cart is currently empty. | |||||||||
| - Coupon Code | |||||||||
We accept the following payment methods as well as pay-by-invoice.
TDS
NCBI
UniProt
Tech Support
Customer Service
