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K1858-46 Anti-KIR2DL3, Recombinant, Human (p58 KIR, CD158, cl-6, KIR-K7, NKAT2, NKR-K7, Killer Cell Immunoglobulin (Ig)-like Receptor)

Specifications
References
Grade
Highly Purified
Shipping Temp
Blue Ice
Storage Temp
-20°C

An inhibitory Killer Cell Ig-like Receptor (KIR, previously called p58 KIR, cl-6, NKAT2 or KIR-K7), which recognizes class I MHC molecules (HLA-Cw1, -Cw3, -Cw7, and Cw8). The protein coding region of the extracellular domain of KIR2DL3 (amino acid 1-202) was cloned into an E. coli expression vector.

Molecular Weight
22.2kD
Sequence
MEGVHRKPSL/ LAHPGPLVKS/ EETVILQCWS/ DVRFQHFLLH/ REGKFKDTLH/ LIGEHHDGIS/ KANFSIGPMM/ QDLAGTYRCY/ GSVTHSPYQL/ SAPSDPLDIV/ ITGLYEKPSL/ SAQPGPTVLA/ GESVTLSCSS/ RSSYDMYHLS/ REGEAHERRF/ SAGPKVNGTF/ QADFPLGPAT/ HGGTYRCFGS/ FRDSPYEWSN/ SSDPLLVSVT/ GN
Storage and Stability
May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Source
Recombinant, E. coli
Purity
≥ 95% by SDS PAGE; Extracellular domain was purified by FPLC gel-filtration chromatography, after refolding of the isolated inclusion bodies in a redox buffer.
Concentration
As reported
Form
Supplied as a liquid in 20mM Tris-HCl, pH 7.5.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Form
Supplied as a liquid in 20mM Tris-HCl, pH 7.5.
Purity
≥ 95% by SDS PAGE; Extracellular domain was purified by FPLC gel-filtration chromatography, after refolding of the isolated inclusion bodies in a redox buffer.
References
1. Steffens, U., et al., Tissue Antigens 51: 398-413 (1998). 2. Wagtmann, N.R., et al., Immunity 2: 439-449 (1995). 3. Colonna, M., et al., Science 268: 405-408 (1995). 4. Kim, J., et al., J. Immunol. 159: 3875-3882 (1997).
USBio References
No references available
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