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M2965-01N Rabbit Anti-Merlin, NT (Moesin-ezrin-radixin-like Protein, ACN, BANF, Neurofibromin 2, Neurofibromin-2, NF2, Schwannomerlin, Schwannomin, SCH)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
P35240
Isotype
IgG
Grade
Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_000259
Shipping Temp
Blue Ice
Storage Temp
-20°C
Bilateral Acoustic Neuroma

Merlin is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This protein has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport.

Applications
Suitable for use in ELISA and Western Blot. Other applications not tested.
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:50-1:100 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic peptide selected from the N-terminal region of human Merlin (KLH).
Form
Supplied as a liquid in PBS, 0.25% sodium azide.
Purity
Purified by ammonium sulfate precipitation.
Specificity
Recognizes human Merlin.
References
1. James,M.F., et.al., Mol. Cell. Biol. 29(15), 4250-4261 (2009).
USBio References
No references available
Conjugates
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