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N2146-01A Mouse Anti-Neuroendocrine Specific Protein A (NSP-A, Rtn 1A, Reticulon 1A)

Specifications
References
Clone Type
Monoclonal
Host
Mouse
Source
Human
Isotype
IgG1
Clone Number
MON161
Grade
Affinity Purified
Applications
IC IHC WB
Crossreactivity
Hm Hu Mo Rt
Shipping Temp
Blue Ice
Storage Temp
-20°C
Notes
BSA Free

Applications
Suitable for use in Immunohistochemistry (frozen and paraffin sections), Immunocytochemistry, and Western Blotting. Other applications not tested.
Recommended Dilutions
Optimum dilutions to be determined by researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Neuroendocrine Specific Protein A (NSP-A, Rtn 1A, Reticulon 1A)
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. No stabilizing proteins added.
Purity
Purified by Protein G affinity chromatography.
Specificity
Neuro-endocrine specific protein (NSP)-A. Reactive with residues 174-337. Species crossreactivity: Human, mouse, rat, hamster.
References
2.  Senden NHM, Timmer EDJ, De Bruïne A, Wagenaar SS, Van de Velde HJK, Roebroek AJM, Van de Ven WJM, Broers JLV, Ramaekers FCS. A comparison of NSP-reticulons with conventional neuroendocrine markers in immunophenotyping of lung cancers. J Pathol. 182: 13-21 (1997). ||3.  Mijnheere EP, Boerman OC, Broers JLV, Klein Rot M, Vooijs GP, Ramaekers FCS. Immunotargeting of human small cell lung cancr xenografts in athymic mice using a monoclonal antibody (RNL-1) against a neuro-endocrine-related antigen. Br J Cancer 63: 78-81 (1991). ||4.  Hens J, Nuydens R, Geerts H, Senden NHM, Van de Ven WJM, Roebroek AJM, Van de Velde HJK, Ramaekers FCS, Broers JLV. Neuronal differentiation is accompanied by NSP-C expression. Cell Tissue Res. 292: 229-237 (1998). ||5.  Senden NHM, Van de Velde HJK, Broers JLV, Timmer EDJ, Kuijpers HJH, Roebroek AJM, Van de Ven WJM, Ramaekers FCS. Subcellular Localization and supramolecular organization of neuroendocrine-specific protein B (NSP-B) in small cell lung cancer. Eur J Cell Biol. 65: 341-353 (1994). ||6.  Senden NHM, Timmer EDJ, Boers JE, Van de Velde HJK, Roebroek AJM, Van de Ven WJM, Broers JLV, Ramaekers FCS. Neuroendocrine-specific protein C (NSP-C) - subcellular localization and differential expression in relation to NSP-A. Eur J Cell Biol. 69: 197-213 (1996). ||7.  Kim H, Yoo BC, Broers JL, Cairns N, Lubec, G. Neuroendocrine-specific protein C, a marker of neuronal differentiation, is reduced in brain of patients with Down syndrome and Alzheimer’s disease. Biochem Biophys Res Commun 276: 329-334 (2000).
USBio References
No references available
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