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N8590-02-FITC Mouse Anti-NY-ESO-1 (FITC)

Specifications
References
Clone Type
Monoclonal
Host
Mouse
Source
Human
Conjugate
FITC
Isotype
IgG1
Clone Number
6A146
Grade
Affinity Purified
Applications
IHC WB
Crossreactivity
Hu
Gene ID
1485
Shipping Temp
Blue Ice
Storage Temp
-20°C
Notes
Preservative Free
BSA Free

NY-ESO-1 is a member of the cancer/testis (CT) family of antigens. Cancer/testis antigens are expressed in a range of malignant neoplasmas such as melanoma and carcinomas of the breast, ovary and lung, but not in normal tissue except in testis. NY-ESO-1 is a classic CT antigen discovered during a SEREX analysis of esophageal cancer. It is a 22-23kD hydrophobic protein.

Applications
Suitable for use in Western Blot and Immunohistochemistry. Other applications have not been tested.
Recommended Dilutions
Optimal dilutions to determined by the researcher.
Storage and Stability
Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Note: Applications are based on unconjugated antibody.
Immunogen
Recombinant protein corresponding to human NY-ESO-1.
Form
Supplied as a liquid in PBS, pH 7.2. No preservatives added. Labeled with Fluorescein isothiocyanate (FITC).
Purity
Purified by affinity chromatography.
Specificity
Recognizes human NY-ESO-1.
References
1. Boon, T., et al., Immunology Today 18: 267-268 (1997). 2. Old, L.J., et al., J. Exp. Med. 187: 1163-1167 (1998). 3. Chen, Y.T., et al., Cytogenet. Cell Genet. 79: 237-240 (1997).
USBio References
No references available
Conjugates
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