Ornithine decarboxylase (ODC), the first enzyme in polyamine synthesis, is a transcriptional target of YC and a modifier of APC -dependent tumorigenesis. It is located to 2p25. There is considerable genetic homology between a region of mouse chromosome 12 and the distal short arm of human chromosome 2. Complete amino acid sequence of human ornithine decarboxylase deduced from complementary DNA.
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