PGC-1 is a transcription factor that determines whether preadipocytes will differentiate into brown or white fat cells. It interacts with PPARg to promote the expression of a cassette of genes which define the brown adipocyte phenotype.

Suitable for use in Western Blot, Immunocytochemistry and FLISA. Other applications have not been tested.

Optimal dilutions to be determined by the researcher.

Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight™550 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Note: Applications are based on unconjugated antibody.

Synthetic peptide corresponding to aa777-797 from the C-terminus of mouse PGC-1. Species Sequence Homology: Human.

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™550.

Purified by Protein A affinity chromatography.

Recognizes mouse PGC-1 (PPARg Coactivator 1). No crossreactivity with other proteins detected. Antibody binding has been inhibited by pre-incubating the antibody with the peptide immunogen.