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P4072-08H Rabbit Anti-PDE8A, ID (L572) (High Affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic Phosphodiesterase 8A)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Purified
Applications
E IHC WB
Crossreactivity
Hu
Accession #
NP_002596; O60658
Shipping Temp
Blue Ice
Storage Temp
-20°C

PDE8A plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase, which has a high affinity for cAMP, may be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development.

Applications
Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested.
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:50-1:100 Immunohistochemistry: 1:50 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic peptide selected from the Center region of human PDE8A (KLH).
Form
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity
Purified by ammonium sulfate precipitation
Specificity
Recognizes human PDE8A.
References
1. Wu,P., Proc. Natl. Acad. Sci. USA 101(51), 17634-17639 (2004). 2. Gamanuma,M., Cell. Signal. 15(6), 565-574 (2003).
USBio References
No references available
Conjugates
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