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S0626-04 Anti-Secretogranin-5, aa27-212, Recombinant, Human (Secretogranin 5, SCG5, Secretogranin V, Secretogranin-V, SgV, 7B2, 7B2 Protein, APPG, Neuroendocrine Protein 7B2, P7B2, Pituitary Polypeptide, Prohormone Convertase Chaperone, Secretory Granule Endocrine Protein I, Secretory Granule Neuroendocrine Protein 1, SGNE1)

Specifications
References
Grade
Purified
Accession #
AAH05349
Shipping Temp
Blue Ice
Storage Temp
-20°C

SCG5, also known as Neuroendocrine protein 7B2, is widely distributed in neuroendocrine tissues. It functions as a chaperone protein for the proprotein convertase PC2 and is required for the production of an active PC2 enzyme.

Source
Recombinant corresponding to aa27-212 of human SCG5 protein, fused to His-tag at C-terminus, expressed in E.coli.
Amino Acid Sequence
MYSPRTPDRV SEADIQRLLH GVMEQLGIAR PRVEYPAHQA MNLVGPQSIE GGAHEGLQHL GPFGNIPNIV AELTGDNIPK DFSEDQGYPD PPNPCPVGKT ADDGCLENTP DTAEFSREFQ LHQHLSDPEH DYPGLGKWNK KLLYEKMKGG ERRKRRSVNP YLQGQRLDNV VAKKSVPHFS DEDKDPELEH HHHHH
Molecular Weight: 22kD (195aa), confirmed by MALDI-TOF
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20°C. Aliquots are stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Source
Recombinant, E. coli
Purity
~85% (SDS-PAGE)
Concentration
~0.5mg/ml
Form
Supplied as a liquid in 25mM Tris, pH 8.0, 0.1M sodium chloride, 1mM DTT, 0.1mM PMSF, 20% glycerol.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Form
Supplied as a liquid in 25mM Tris, pH 8.0, 0.1M sodium chloride, 1mM DTT, 0.1mM PMSF, 20% glycerol.
Purity
~85% (SDS-PAGE)
References
1. Mbikay M.., et al. (2001) Biochem. J. 357: 329-42. 2. Taupenot L, et al. (2003) N Engl J Med. 348(12): 1134-49.
USBio References
No references available
Conjugates
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