Mouse SF20 is a secreted bone marrow stroma-derived growth factor. SF20 isnot only expressed in bone marrow and spleen stroma cells, It is expressed in resting mononuclear cells, resting CD8+ and CD19+ cells and activated CD8+ T cells. It has been shown only to bind to the surface of cells expressing the receptor TSA-1 (Thymic shared Ag-1). Reports show that SF20 stimulates the proliferation of FDCP2 (a mouse IL-3 factor-dependent hemopoietic cell line) cells and mouse lymphoid cells through TSA-1, but it does not show any myelopoietic activity. More research on SF20 and its receptor TSA-1 may help determine the role they play in the regulation of lymphocyte activation. Recombinant Mouse SF20 is a 15.8kD protein, consisting of 143 amino acid residues.

Suitable for use in FLISA and Western Blot. Other applications not tested.

Optimal dilution determined by the researcher.

Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight™550 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Note: Applications are based on unconjugated antibody.

Recombinant protein corresponding to mouse SF-20 expressed in E. coli.

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™550.

Purified by immunoaffinity chromatography.

Recognizes mouse SF-20.