Slug controls the expression of a wide variety of genes including TP53, BRCA2, PUM and CDH1, and has important roles in apoptosis and epithelial-mesenchymal transition. It is also thought to function in neural crest development. Slug expression in breast, oesophageal, and colorectal carcinomas has been correlated with poor prognosis for survival.

Suitable for use in Western Blot. Other applications not tested.

Western Blot: 0.5-2ug/m Optimal dilutions to be determined by the researcher.

May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

A 13aa peptide sequence near the center of human Slug.

Supplied as a liquid in PBS, 0.02% sodium azide.

Purified by immunoaffinity chromatography.

Recognizes human Slug at ~30kD in 293 cell lysate. Does not react with Snail. Species Crossreactivity: mouse.