EDG3, NT

Clone Type

Polyclonal

Host

Rabbit

Source

Human

Swiss Prot

Q99500

Isotype

IgG

Grade

Purified

Applications

E WB

Crossreactivity

Hu Mo

Shipping Temp

Blue Ice

Storage Temp

-20°C

EDG3 is a member of the EDG family of receptors, which are G protein-coupled receptors. This protein has been identified as a functional receptor for sphingosine 1-phosphate and likely contributes to the regulation of angiogenesis and vascular endothelial cell function.

Applications

Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilutions

Western Blot: 1:1000 Optimal dilutions to be determined by the researcher.

Storage and Stability

May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunogen

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 1-30 in the N-terminal region of human EDG3

Form

Supplied as a liquid in PBS, 0.09% sodium azide.

Purity

Purified by ammonium sulfate precipitation

Specificity

Recognizes human EDG3. Species Crossreactivity: mouse

References

1. Licht, T., et al., Blood 102(6):2099-2107 (2003). 2. Himmel, H.M., et al., Mol. Pharmacol. 58(2):449-454 (2000). 3. An, S., et al., J. Biol. Chem. 275(1):288-296 (2000). 4. Ancellin, N., et al., J. Biol. Chem. 274(27):18997-19002 (1999). 5 .Lee, M.J., et al., Cell 99(3):301-312 (1999).

USBio References

No references available

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S5451-02 Rabbit Anti-EDG3, NT (Sphingosine 1-phosphate Receptor 3, S1P Receptor 3, S1P3, Endothelial Differentiation G-protein Coupled Receptor 3, Sphingosine 1-phosphate Receptor Edg-3, S1P Receptor Edg-3, S1PR3)

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