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T5400-43U Goat Anti-Thyroid Stimulating Hormone, beta (Thyroid-stimulating Hormone Subunit beta, TSH beta, TSH-beta, TSHb, TSH-B, Thyrotropin alfa, Thyrotropin beta Chain, Thyrotropin Subunit beta)

Specifications
Clone Type
Polyclonal
Host
Goat
Source
Human
Swiss Prot
P01222
Isotype
IgG
Grade
Affinity Purified
Applications
E
Crossreactivity
Hu
Shipping Temp
Blue Ice
Storage Temp
-20°C

Thyroid-stimulating hormone (TSH or thyrotropin), produced in human pituitary glands, has a molecular mass of 25kD. An Important indicator of thyroid function, TSH is used to monitor thyroid associated diseases. Thyroid-stimulating hormone is a hormone synthesized and secreted by thyrotrope cells in the anterior pituitary gland which regulates the endocrine function of the thyroid gland. TSH stimulates the thyroid gland to secrete the hormones thyroxine (T4) and triiodothyronine (T3). TSH production is controlled by a Thyrotropin Releasing Hormone (TRH), which is manufactured in the hypothalamus and transported to the anterior pituitary gland, where it increases TSH production and release. Somatostatin is also produced by the hypothalamus, and has an opposite effect on the pituitary production of TSH, decreasing or inhibiting its release.

Applications
Suitable for use in ELISA. Other applications not tested.
Recommended Dilutions
Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
TSH (intact) from human pituitary glands
Form
Supplied as a liquid in PBS, pH 7.2, 0.05% sodium azide
Purity
Purified by immunoaffinity chromatography
Specificity
Recognizes human TSH, B subunit.
Conjugates
Pricing
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