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010211 3',4'-Dimethoxy-α-naphthoflavone CAS: 14756-24-2

Specifications
References
CAS Number
14756-24-2
Grade
Highly Purified
Molecular Formula
C21H16O4
Molecular Weight
332.35
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
RT
DiMNF; 2-(3,4-Dimethoxyphenyl)-benzo[h]chromen-4-one, NSC 123391; 2-(3,4-Dimethoxyphenyl)-4H-naphtho[1,2-b]pyran-4-one;

3',4'-Dimethoxy-α-naphthoflavone (DiMNF) is a potent and selective aryl hydrocarbon receptor (AHR) modulator (SAhRM). Studies show that DiMNF suppresseses cytokine-mediated complement factor gene expression through selective activation of the Ah receptor. DiMNF has therapeutic potential in regulating the immune response to tumor formation.

References
Murray, I.A. et al.: Mol. Pharmacol., 79, 508 (2011); Narayanan, G.A. et al.: J. Pharmacol. Exp. Ther., 342, 345 (2012);
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