1,5-Isoquinolinediol CAS 5154-02-9

CAS Number

5154-02-9

Grade

Highly Purified

MDL Number

MFCD00006900

Molecular Formula

C9H7NO2

Molecular Weight

161.12

EU Commodity Code

38220090

Shipping Temp

Blue Ice

Storage Temp

+4°C/+4°C

5-Hydroxy-1(2H)-isoquinolinone, 1,5-Dihydroxyisoquinoline

PARP-1 inhibitor. Neuroprotectant. Blocks nitric oxide-induced neuronal toxicity. Potent iNOS (inducible nitric oxide synthase/NOS II) inhibitor. Stimulates homologous recombination.

CAS Number

5154-02-9

Molecular Weight

161.12

Molecular Formula

C9H7NO2

Solubility

DMSO or methanol; insoluble in water.

Storage and Stability

Store at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Important Note

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Toxicity and Hazards

All products should be handled by qualified personnel only, trained in laboratory procedures.

References

1. Specific inhibitors of poly(ADP-ribose) synthetase and mono(ADP-ribosyl)transferase: M. Banasik, et al.; J. Biol. Chem. 267, 1569 (1992)|2. Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity: J. Zhang, et al.; Science 263, 687 (1994)|3. Inhibition of NOS-2 induction in LPS-stimulated J774.2 cells by 1, 5-isoquinolinediol, an inhibitor of PARP: R. Olszanecki, et al.; J. Physiol. Pharmacol. 57, 109 (2006)|4. 1,5-isoquinolinediol increases the frequency of gene targeting by homologous recombination in mouse fibroblasts: A. Semionov, et al.; Biochem. Cell Biol. 81, 17 (2003)

USBio References

No references available

Product	Size	List	Your Price	Qty	Ext Price
Subtotal:	Subtotal:
Subtotal:	Subtotal:
Total Coupon Savings:	Total Coupon Savings:	()
Your cart is currently empty.
- Coupon Code

Product

Size

List

Your Price

Qty

Ext Price

Subtotal:

Total Coupon Savings:

()

Your cart is currently empty.

- Coupon Code

044432 1,5-Isoquinolinediol CAS: 5154-02-9

CAS Number

Grade

MDL Number

Molecular Formula

Molecular Weight

EU Commodity Code

Shipping Temp

Storage Temp

5-Hydroxy-1(2H)-isoquinolinone, 1,5-Dihydroxyisoquinoline

References

USBio References

Pricing

Order

Cart Summary

Recently Viewed

Special Offers

Contact Us

Site Map

Technical Resources

Distributors

Payment Methods