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045107 NSC697923 CAS: 343351-67-7

Specifications
References
CAS Number
343351-67-7
Grade
Highly Purified
MDL Number
MFCD01925132
Molecular Formula
C₁₁H₉NO₅S
Molecular Weight
267.3
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
-20°C
2-[(4-Methylphenyl)sulfonyl]-5-nitro-Furan, 2-Nitro-5-tosylfuran

Selective Ub-conjugating enzyme (E2) complex Ubc13-Uev1A inhibitor. Inhibits the formation of the Ubc13~Ub conjugate. NF-kB activation inhibitor. Inhibits proliferation and survival of ABC-DLBCL and GCB-DLBCL (Diffuse large B cell lymphoma) cells.

Synonyms
2-[(4-Methylphenyl)sulfonyl]-5-nitro-Furan, 2-Nitro-5-tosylfuran
CAS Number
343351-67-7
Molecular Weight
267.3
Molecular Formula
C₁₁H₉NO₅S
Solubility
DMSO
Method for Determining Identity
Proton NMR
Appearance
Supplied as a white solid.
Purity
≥98% (NMR)
Storage and Stability
Store at 4°C short term storage. Stable for 12 months after receipt when stored at -20°C. Protect from light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Toxicity and Hazards
 All products should be handled by qualified personnel only, trained in laboratory procedures.
References
1. Inhibition of proliferation and survival of diffuse large B-cell lymphoma cells by a small-molecule inhibitor of the ubiquitin-conjugating enzyme Ubc13-Uev1A: M. Pulvino, et al.; Blood 120, 1668 (2012).
USBio References
No references available
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