CAS 294646-77-8

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045187 (R)-CR8 (2-(R)-(1-Ethyl-2-hydroxyethylamino)-6-(4-(2-pyridyl)benzyl)-9-isopropylpurine) CAS: 294646-77-8

Specifications

References

CAS Number

294646-77-8

Grade

Highly Purified

Molecular Formula

C24H29N7O

Molecular Weight

431.5

EU Commodity Code

38220090

Shipping Temp

Blue Ice

Storage Temp

4°C/-20°C

2-(R)-(1-Ethyl-2-hydroxyethylamino)-6-(4-(2-pyridyl)benzyl)-9-isopropylpurine

Potent and selective cyclin-dependent kinase (CDK) 1, 2, 5, 7 and 9 inhibitor. Apoptosis inducer. Potent glycogen synthase kinase (GSK-3alpha/beta) inhibitor.

Storage and Stability

Short-term Storage: +4°C Long-term Storage: -20°C Stable for at least 2 years after receipt when stored at -20°C.

Purity

>98% (NMR)

Important Note

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

References

Product Reference: |●CR8, a potent and selective, roscovitine-derived inhibitor of cyclin-dependent kinases: K. Bettayeb, et al.; Oncogene 27, 5797 (2008)|●