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045273 SB366791 (N-(3-Methoxyphenyl)-4-chlorocinnamide) CAS: 472981-92-3

Specifications
References
CAS Number
472981-92-3
Grade
Highly Purified
MDL Number
MFCD01033818
Molecular Formula
C16H14ClNO2
Molecular Weight
287.8
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
4°C
N-(3-Methoxyphenyl)-4-chlorocinnamide

Potent and selective TRPV1 antagonist. Glutamatergic synaptic transmission inhibitor.

Synonyms
N-(3-Methoxyphenyl)-4-chlorocinnamide
CAS Number
472981-92-3
Molecular Formula
C16H14ClNO2
Molecular Weight
287.8
Solubility
100% ethanol (warm) or DMSO.
Appearance
Supplied as a white to beige crystalline solid.
Purity
≥99% (NMR)
Storage and Stability
Store at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
References
Product Reference: |●Identification and characterisation of SB-366791, a potent and selective vanilloid receptor (VR1/TRPV1) antagonist: M.J. Gunthorpe, et al.; Neuropharmacology 46, 133 (2004)|●Effects of the novel TRPV1 receptor antagonist SB366791 in vitro and in vivo in the rat: A. Varga, et al.; Neurosci. Lett. 385, 137 (2005)|●TRPV1 antagonist, SB-366791, inhibits glutamatergic synaptic transmission in rat spinal dorsal horn following peripheral inflammation: S.C. Lappin, et al.; Eur. J. Pharmacol. 540, 73 (2006)|●
USBio References
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