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045283 SIN-1 chloride (3-Morpholinosydnonimine, Linsidomine) CAS: 16142-27-1

Specifications
References
CAS Number
16142-27-1
Grade
Highly Purified
Molecular Formula
C6H11ClN4O2
Molecular Weight
206.6
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C
3-Morpholinosydnonimine, Linsidomine

Nitric oxide (NO) donor. Generates both superoxide anion and nitric oxide that spontaneously form peroxynitrite. Platelet aggregation inhibitor. Guanylyl cyclase activator. Cytotoxic. Positive ionotropic. Vasodilator.

CAS Number
16142-27-1
Molecular Formula
C6H11ClN4O2
Molecular Weight
206.6
Solubility (>5mg/ml)
Ethanol (100%), water or DMSO
Method for Determining Identity
Proton NMR
Storage and Stability
Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Prepare fresh as needed. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Purity
≥98% (NMR)
Form
Supplied as a white solid.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
References
1. N. Hogg et al.; Biochem. J. 281:419 (1992) 2. M. Nishikawa et al.; J. Phar.macol. Exp. Ther. 220:183 (1982) 3. M. Spiecker, et al.; Thromb. Res. 70:405 (1993) 4. K. Konishi, et al.; Nitric Oxide 20:270 (2009) 5. M.J. Kohr, et al.; J. Mol. Cell. Cardiology 48:645 (2010) 6. W. Schulz & G. Kober; Basic Res. Cardiol. 86:233 (1991)
USBio References
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