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366893 KY02111 CAS: 1118807-13-8

Specifications
References
CAS Number
1118807-13-8
Grade
Highly Purified
MDL Number
MFCD08483062
Molecular Formula
C18H17ClN2O3S
Molecular Weight
376.9
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C
KY 02111, KY-02111, CHEMBL3186128, HY-13815, S-7828

Synonyms
KY 02111, KY-02111, CHEMBL3186128, HY-13815, S-7828
Chemical Name
N-(6-chloro-1,3-benzothiazol-2-yl)-3-(3,4-dimethoxyphenyl)propanamide
Molecular Formula
C18H17ClN2O3S
Molecular Weight
376.9
CAS Number
1118807-13-8
Purity
≥95%
Applications
FA
Appearance: Crystalline solid
Description
KY02111 is a Wnt signaling inhibitor that functions through a mechanism distinct from Endo-IWR-1, IWP-2, and IWP-4. It is used to promote the differentiation of human pluripotent stem cells to cardiomyocytes.
Storage
Soluble in organic solvents such as DMSO. DMSO up to 25mM.
Purity
≥95%
Form
Supplied as a crystalline solid.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
References
1. Nakatsuji, N., Kawase, E., Miyazaki, T., Minami, I., Aiba, K. (2013). Multidisciplinary research of human pluripotent stem cells for application to cell therapy and drug discovery. Tissue Engineering and Regenerative Medicine,10(4), 160-163. 2. Morgan, J. T., Raghunathan, V. K., Chang, Y. R., Murphy, C. J., Russell, P. (2015). Wnt inhibition induces persistent increases in intrinsic stiffness of human trabecular meshwork cells. Experimental eye research, 132, 174-178. 3. Li, W., Li, K., Wei, W., Ding, S. (2013). Chemical approaches to stem cell biology and therapeutics. Cell stem cell, 13(3), 270-283.
USBio References
No references available
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