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036737 HOXD8, CT (HOXD8, HOX4E, Homeobox protein Hox-D8, Homeobox protein Hox-4E, Homeobox protein Hox-5.4)

Specifications
References
Specificity
Human
Source Antibody
human
Purity
Purified by Protein A affinity chromatography.
Gene ID
3234
Gene #
HOXD8
Accession Number
NP_062458.1
EU Commodity Code
30021010
Shipping Temp
Blue Ice
Storage Temp
-20°C
HOXD8, HOX4E, Homeobox protein Hox-D8, Homeobox protein Hox-4E, Homeobox protein Hox-5.4

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. In addition to effects during embryogenesis, this particular gene may also play a role in adult urogenital tract function.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
References
Ester, A.R., et al. Am. J. Med. Genet. A 149A (12), 2745-2752 (2009) :|Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)|Harada, K., et al. J. Cell. Sci. 122 (PT 21), 3923-3930 (2009) :|Goodman, F.R. Am. J. Med. Genet. 112(3):256-265(2002)|Kosaki, K., et al. Teratology 65(2):50-62(2002)
USBio References
No references available
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