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040911 RBP4, NT (RBP4, Retinol-binding protein 4, Plasma retinol-binding protein, Plasma retinol-binding protein(1-182), Plasma retinol-binding protein(1-181), Plasma retinol-binding protein(1-179), Plasma retinol-binding protein(1-176))

Specifications
References
Specificity
Mouse
Source Antibody
mouse
Purity
Purified by Protein A affinity chromatography.
Gene ID
5950
Gene #
RBP4
Accession Number
NP_006735.2
EU Commodity Code
30021010
Shipping Temp
Blue Ice
Storage Temp
-20°C
RBP4, Retinol-binding protein 4, Plasma retinol-binding protein, Plasma retinol-binding protein(1-182), Plasma retinol-binding protein(1-181), Plasma retinol-binding protein(1-179), Plasma retinol-binding protein(1-176)

This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
References
Wang, S.N., et al. J. Formos. Med. Assoc. 109(6):422-429(2010)|Liu, X.H., et al. Zhonghua Yi Xue Za Zhi 90(18):1251-1254(2010)|Ku, Y.H., et al. J. Int. Med. Res. 38(3):782-791(2010)|Giacomozzi, C., et al. J. Endocrinol. Invest. 33(4):218-221(2010)|Nair, A.K., et al. PLoS ONE 5 (7), E11444 (2010) :
USBio References
No references available
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