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044919 IL-33 (human) BioAssay™ ELISA Kit (NF-HEV, Interleukin-33, IL-1F11)

Specifications
Brand
BioAssay™
Specificity
Detects human IL-33. Does not cross-react with mouse IL-33, human IL-6, human IL-24, human IL-23, human IL-17A or human ST2.
Kit Type
ELISA
Tests
96
Sensitivity
5pg/ml
Detection Method
Colorimetric
Detection Range
0.016-1ng/ml
Sample Matrix
Serum
EU Commodity Code
38220000
UN DOT Shipping
UN2796 PGII
Shipping Temp
Blue Ice
Storage Temp
+4°C/+4°C
NF-HEV, Interleukin-33, IL-1F11

Interleukin-33 (IL-33; HF-NEV; IL-1F11), a member of the IL-1 family of cytokines, is expressed by many cell types following pro-inflammatory stimulation and is thought to be released on cell lysis. IL-33 affects the various cell types that express membrane ST2, which is selectively expressed by Th2 but not Th1 cells. The ability of IL-33 to target numerous immune cell types, like Th2-like cells, mast cells, and B1 cells, and to induce cytokine and chemokine production underlines its potential in influencing the outcome of a wide range of diseases, such as arthritis, asthma, atopic allergy & anaphylaxis, cardiovascular disease/atherosclerosis, nervous system diseases, and sepsis. In healthy human serum almost no IL-33 could be detected, whereas serum IL-33 levels were significantly increased in chronic active inflammation, like rheumatoid arthritis.

Storage and Stability
Short-term Storage: +4°C Long-term Storage: +4°C
Specificity
Detects human IL-33. Does not cross-react with mouse IL-33, human IL-6, human IL-24, human IL-23, human IL-17A or human ST2.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
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