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301830 Adrenomedullin Ac amide, aa16-21, Human

Specifications
References
Purity
~95% (HPLC)
EU Commodity Code
30021019
Shipping Temp
Blue Ice
Storage Temp
4°C

Calcitonin, calcitonin gene-related peptide (CGRP), adrenomedullin (ADM), and amylin belong to a unique group of peptide hormones important for homeostasis in diverse tissues. Calcitonin is essential for calcium balance whereas CGRP and ADM are important for neurotransmission, and cardiovascular and respiratory regulation.

Source
aa16-21, Human
Molecular Weight
~724.86
Sequence
Ac-Cys-Arg-Phe-Gly-Thr-Cys-NH2, Disulfide Bridge: Cys2-Cys7
Storage and Stability
Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Purity
~95% (HPLC)
Form
Supplied as a white powder.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
References
1. Elicits a hypertensive effect - Watanabe et al. Biochem Biophys Res Commun. 1996 Feb 6;219(1): 59-63. 2. Allaker et al. Interaction ofadrenomedullin and calcitonin gene-related peptide with the periodontal pathogen Porphyromonas gingivalis FEMS Immunol Med Microbiol. 2007 Feb;49(1):91-7. 3. Allaker et al. Mechanisms of adrenomedullin antimicrobial action. Peptides. 2006 Apr;27(4):661-6.
USBio References
No references available
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