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302511 Jag1 (Protein Jagged-1, Jagged1, CD339, Jag1)

Specifications
References
Specificity
Recognizes mouse Jag1. Species Crossreactivity: mouse
Source Antibody
mouse
Purity
Purified by Protein A affinity chromatography.
Gene ID
16449
Gene #
Jag1
EU Commodity Code
30021010
Shipping Temp
Blue Ice
Storage Temp
-20°C

Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation (By similarity). May regulate fibroblast growth factor-induced angiogenesis.

Applications
Suitable for use in Western Blot. Other applications not tested.
Recommended Dilution
Western Blot: 1:2000 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
References
Shimizu K.,et al.J. Biol. Chem. 274:32961-32969(1999).|Loomes K.M.,et al.Hum. Mol. Genet. 8:2443-2449(1999).|
USBio References
No references available
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