USBio Logo

302518 KDM6A (Lysine-specific Demethylase 6A, 11411-, Histone Demethylase UTX, Ubiquitously-Transcribed TPR Protein on the X Chromosome, Ubiquitously-Transcribed X Chromosome Tetratricopeptide Repeat Protein, KDM6A, UTX)

Specifications
References
Specificity
Recognizes human KDM6A. Species Crossreactivity: human
Source Antibody
human
Purity
Purified by Protein A affinity chromatography.
Gene ID
7403
Gene #
KDM6A
EU Commodity Code
30021010
Shipping Temp
Blue Ice
Storage Temp
-20°C

Histone demethylase that specifically demethylates 'Lys- 27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Demethylation of 'Lys-27' of histone H3 is concomitant with methylation of 'Lys-4' of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A.

Applications
Suitable for use in Western Blot. Other applications not tested.
Recommended Dilution
Western Blot: 1:2000 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
References
Lahn B.T.,et al.Science 278:675-680(1997).|Ross M.T.,et al.Nature 434:325-337(2005).|Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.|Cho Y.-W.,et al.J. Biol. Chem. 282:20395-20406(2007).|Lan F.,et al.Nature 449:689-694(2007).|
USBio References
No references available
Pricing
Order
Proceed to Checkout
Cart Summary
ProductSizeListYour PriceQtyExt Price
Subtotal:Subtotal:
Subtotal:Subtotal:
Total Coupon Savings:Total Coupon Savings:()
Your cart is currently empty.
- Coupon Code
Recently Viewed
  • Contact Us

    Visit our technical library or contact our support staff to answer your questions.

    Telephone:
    1-800-520-3011

    Library | Contact

    Distributors

    For customers outside of the United States, please use one of our many distributors.

    View Distributors

    Payment Methods

    We accept the following payment methods as well as pay-by-invoice.

    MasterCard Visa PayPal
    © 2023-2024 United States Biological - All Rights Reserved