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302569 MRPL17 (39S Ribosomal Protein L17, Mitochondrial, L17mt, MRP-L17, LYST-interacting Protein 2, MRPL17, LIP2)

Specifications
References
Specificity
Recognizes MRPL17. Species Crossreactivity: human, mouse
Source Antibody
human
Purity
Purified
Gene ID
63875
Gene #
MRPL17
EU Commodity Code
30021010
Shipping Temp
Blue Ice
Storage Temp
-20°C

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq, Jul 2008].

Applications
Suitable for use in Western Blot. Other applications not tested.
Recommended Dilution
Western Blot: 1:1000 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
References
Hu R.-M.,et al.Proc. Natl. Acad. Sci. U.S.A. 97:9543-9548(2000).|Tchernev V.T.,et al.Mol. Med. 8:56-64(2002).|Ota T.,et al.Nat. Genet. 36:40-45(2004).|Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.|Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.|
USBio References
No references available
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