ADAM-17, which is also known as CD156b, is expressed in a wide range of cells in culture. Its biological role is to convert the transmembrane trimeric form of TNF alpha to the soluble form. CD156 is also reported to process a number of other proteins, including L-selectin and TNF p75 receptor.

Suitable for use in Western Blot. Other applications have not been tested.

Western Blot: 1:500 Optimal dilutions to be determined by researcher.

Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight™650 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. m

Note: Applications are based on unconjugated antibody.